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KMID : 1144120180080030267
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Biomedical Engineering Letters
2018 Volume.8 No. 3 p.267 ~ p.272
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Mechanical properties and cytotoxicity of PLA/PCL films
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Jeong Hee-Seok
Rho Jeong-Won
Shin Ji-Yeon
Lee Deuk-Yong
Hwang Tae-Seon
Kim Kwang-J.
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Abstract
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Thermodynamically immiscible poly(lactic acid) (PLA) and poly(ε-caprolactone) (PCL) were blended and solution-cast by adding the 3% compatibilizer (tributyl citrate, TBC) of the PCL weight. In the PLA/PCL composition range of 99/1?95/5 wt%, mechanical properties of the PLA/PCL films with TBC were always superior to those of the films without TBC. The tensile strength of 42.9?±?3.5 MPa and the elongation at break of 10.3?±?2.7% were observed for the 93/7 PLA/PCL films without TBC, indicating that PCL addition is effective for strength and ductility. However, the tensile strength of 54.1?±?3.4 MPa and the elongation at break of 8.8?±?1.8% were found for the 95/5 PLA/PCL with TBC, indicating that the effect of co-addition of PCL and TBC on mechanical properties of the films is more pronounced. No cytotoxicity was observed for the PLA/PCL films regardless of TBC addition.
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KEYWORD
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Poly(lactic acid), Poly(ε-caprolactone), Compatibilizer, Tensile strength, Cytotoxicity, Cell proliferation
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